Azitrox 500 Mg

Description

Azitrox 500 mg film-coated tablets
azithromycin
Read all of this leaflet carefully before you start taking this medicine.
because it contains important information for you.
– Keep this leaflet. You may need to read it again .
– If you have any further questions, ask your doctor or pharmacist.
– This medicine has been prescribed for you only. You should not pass it on to others.
It may harm them, even if their signs of illness are the same as yours.
– If you get any side effects, talk to your doctor or pharmacist.
These include any possible side effects not listed in this leaflet. See section 4.
What you will find in this leaflet:
1. What Azitrox is and what it is used for
2. What you need to know before you use Azitrox
3. How to use Azitrox
4. Possible side effects
5. How to store Azitrox
6. Contents of the pack and other information
1. What Azitrox is and what it is used for
Azitrox is an antibiotic indicated for the treatment and prevention of infections. It belongs to the class
macrolide antibiotics, called azalides. It is effective against a broad spectrum of bacteria that can
cause infections.
The medicine can be used to treat the following infections:
– upper respiratory tract infections: bacterial infections of the pharynx, tonsils,
adjacent nasal sinuses and middle ear;
– lower respiratory tract infections: infections of the bronchi and lungs;
– skin and soft tissue infections: moderate acne vulgaris, erythema migrans (first phase of
Lyme disease – possible infection following a bite caused by an infected tick), erysipelas,
bacterial vesicular dermatological disease and secondary suppurative dermatological infections .
2. What you need to know before you use Azitrox
Do not take Azitrox
– if you are allergic to azithromycin, other macrolides or any of the other ingredients
of this medicine (listed in section 6);
– if the patient is a child with a body weight below 25 kg.
– if you have severe liver damage.
Warnings and precautions
Before taking Azitrox, talk to your doctor or pharmacist.
In the case of this pharmaceutical form, the medicine is intended for children over 6 years of age.
Tell your doctor before you start using this medicine:
– if you have liver problems : your doctor may need to
monitor your liver function or interrupt your treatment.
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– if you have kidney problems;
– if you develop diarrhea or notice other signs of infection during treatment;
– if you have low levels of potassium or magnesium in your blood ;
– if you have had heart rhythm disorders : abnormal heartbeat (ventricular arrhythmia), decreased
heart rate (bradycardia ), history of long QT syndrome (in
especially if you are a woman or an elderly person);
– if you have myasthenia gravis.
The drug should be administered with caution to patients with mild to moderate impairment of
liver.
Azitrox with other medicines
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
any other medications.
Azitrox and other medicines can influence each other.
Antacids decrease the rate of absorption of azithromycin, therefore azithromycin should be administered with 1
hour before or 2 hours after taking antacids.
This medicine should not be used concomitantly with ergot derivatives, e.g. ergotamine,
dihydroergotamine (used to treat migraine): ergotism (manifested by
itching of the limbs, muscle cramps and gangrene of the hands and feet as a result of
insufficient blood circulation ).
Azitrox 500 mg can be administered concomitantly with the following medicines only if indicated by a doctor:
medic:
– zidovudine (medicine used to treat HIV infection)
– rifabutin (for the treatment of tuberculosis)
– ciclosporin (used to suppress the immune system to prevent and treat rejection)
a transplanted organ or bone marrow)
– digoxin (used to treat impaired heart pump function)
– warfarin (used to prevent blood clots)
– other antibiotics (such as erythromycin , lincomycin and clindamycin )
– cisapride (used to treat stomach problems), terfenadine (used to treat
allergic conditions including hay fever), antipsychotics (for mental problems), such as
pimozide, antidepressants (for the treatment of depression) such as citalopram, fluoroquinolones
(antimicrobial medicines used to treat infections ), such as moxifloxacin and
levofloxacin, some drugs for the treatment of heart rhythm disorders : the use
Taking these medicines together with Azitrox can cause heart problems.
Macrolide antibiotics (similar to azithromycin ) are known to interact with astemizole and
alfentanil, therefore caution is recommended when co-administering these drugs with azithromycin.
medicines.
Azitrox with food and drink
Azitrox is administered once a day, at least 1 hour before a meal, or 2 hours after a meal.
Pregnancy, breastfeeding and fertility
If you are pregnant or breast-feeding , think you may be pregnant or are planning to become pregnant,
Ask your doctor for advice before taking this medicine.
Pregnant or breastfeeding women should take Azitrox only if absolutely necessary, at
doctor’s recommendation.
Driving and using machines
There are no data available on the effect of Azitrox 500 mg on the ability to drive and use machines.
to use machinery.
3. How to take Azitrox
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Always take this medicine exactly as your doctor or pharmacist has told you.
Talk to your doctor or pharmacist if you are not sure.
Adults and children weighing over 45 kg
Azithromycin is administered once a day, at least 1 hour before a meal or 2 hours after a meal.
In case of respiratory tract infections the recommended dose is 500 mg of azithromycin, once a day for
for three days.
Moderate acne vulgaris
In the treatment of moderate acne vulgaris, a total dose of 6 g is recommended , in the following regimen:
therapeutic: one 500 mg tablet once a day for 3 days, followed by one 500 mg tablet once a day for 3 days
once a week for 9 weeks. From the second week, the dose should be administered every seven days
from the first tablet, and the next 8 doses should be administered at 7-day intervals.
Erythema chronicum migrans
On the first day, the recommended dose is 1 g of azithromycin (two Azitrox 500 mg tablets in a
single dose); on days 2-5 the recommended dose is 500 mg of zithromycin daily (one tablet of
Azitrox 500 mg).
Sexually transmitted diseases
The recommended dose is 1 g (two Azitrox 500 mg tablets ).
Children weighing less than 45 kg
In the case of this pharmaceutical form, the medicine is intended for children over 6 years of age.
Azithromycin is administered once a day, at least 1 hour before a meal or 2 hours after a meal.
In the case of respiratory tract infections , the recommended dose is 10 mg/kg once a day for three days.
In the case of chronic migratory erythema (first phase of Lyme disease), the doses are as follows: on the first day,
Children are given 20 mg/kg once every 24 hours, and on days 2-5 10 mg/kg once every 24 hours.
Patients with kidney or liver disease
You should tell your doctor if you have kidney or liver problems because
Your doctor may need to change your usual dose.
Azitrox is administered once a day, at least 1 hour before a meal, or 2 hours after a meal.
The film-coated tablets should be swallowed whole.
If you take more Azitrox than you should
If you take too many tablets at the same time, contact your doctor immediately. Show them
The remaining tablets. Adverse reactions occurring at doses higher than those recommended were
similar to those observed at usual doses. Overdose of macrolide antibiotics is manifested by
reversible hearing loss, severe nausea, vomiting and diarrhoea. In case of overdose, contact your doctor immediately.
immediately to your doctor or the nearest hospital emergency department .
If you forget to take Azitrox
If you forget to take a tablet, take it as soon as possible . Take the next dose at the usual time .
24 hours.